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In a large, prospective randomized trial, use of MCBT to guide combination antimicrobial therapy did not result in better clinical and bacteriologic response compared to standard culture and sensitivity testing in a group of 251 patients with routine exacerbations of cystic fibrosis associated with multiply-resistant
All patients were also assessed for Burkholderia cepacia respiratory colonization during ICU hospitalization. In case-patients, time and possible sources of bacteremia, antimicrobial susceptibility and response to therapy were also recorded. A B.cenocepacia bacteremia case was defined as any ICU inpatient with at least
Burkholderia cepacia complex (BCC) is an important nosocomial pathogen in hospitalised patients, particularly those with prior broad-spectrum antibacterial therapy. BCC causes infections that include bacteraemia, urinary tract infection, septic arthritis, peritonitis and respiratory tract infection. Due to high intrinsic resistance
29 Jun 2007 Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study. Bressler AM(1), Kaye KS, LiPuma JJ, Alexander BD, Moore CM, Reller LB, Woods CW. Author information: (1)Infectious Disease Specialists of Atlanta and Clinical
11. DOF. [Agreement that establishes the guidelines that shall be followed to sale and dispense antibiotics. Ministry of Health. failure and pulmonary edema developed Burkholderia bacteremia. She was treated according to bacterial sensitivity with no attrib- utable consequences. Several days later, a second patient in
Guideline. Cystic Fibrosis- Management of. Burkholderia cepacia complex infections. Key messages. Burkholderia cepacia infections are associated with significant adverse outcomes in. Cystic Fibrosis patients. Spread of infection can be limited by strict infection control measures. Early and aggressive combination
27 Jun 2016 Symptoms of B. cepacia infection. The effects of B. cepacia on people vary widely, ranging from no symptoms at all to serious respiratory infections, especially in patients with cystic fibrosis. Electron Micrograph of Burkholderia cepacia. For more images of this bacterium, search the Public Health Image
Outbreak of Burkholderia cepacia Bacteremia in a Pediatric Hospital Due to Contamination of Lipid Emulsion Stoppers Blood grown in cultures (FAN Aerobie; Biomerieux, Marcy l'Etoile, France) on day 6 of life grew B. cepacia, and the infant was successfully treated with ceftazidime (100 mg/kg of body weight/day for 10
27 Oct 2015 Patient-to-patient spread of B cepacia may be minimized and/or prevented with effective infection-control measures. Use Foley catheters only as long as necessary. If possible, avoid their use in compromised hosts predisposed to urinary tract infections (eg, patients with diabetes, SLE, multiple myeloma).
Fifty-three patients with B. cepacia complex bacteremia were identified; only 9 (17%) had cystic fibrosis. Twenty-five patients (47%) died within 14 days of bacteremia. After controlling for comorbid conditions and therapeutic interventions, 2 outbreak-related strains of Burkholderia cenocepacia (genomovar III) were
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